2013 Wrangler Sport, 4WD, 2 Door, automatic transmission, manual locks and windows, no security system.

What happened:
I’m driving 75MPH on the interstate and it shuts down completely. No warning, no lights, no dings.

It will not start. Engine light flashes, lightning bolt flashes, red dot above the temperature gauge flashes.

U0100 Code - No communication with the engine controller (CAN)
U110B Code - Lost coolant

I replaced the PCM, it was programmed to my VIN.
I have verified the battery is fine, checked all grounds and cleaned all connectors.

Nothing.

Please help!